Codeine is an alkaloid obtained from opium or prepared from morphine by methylation and occurs as white crystals. Codeine effloresces slowly in dry air and is effected by light.
Each soluble tablet contains 30 mg (0.074 mmol) or 60 mg (0.15 mmol) of codeine phosphate. These tablets also contain lactose and sucrose.
Soluble tablets of codeine phosphate are freely soluble in water. They are intended for the preparation of solutions for parenteral administration. These tablets are not sterile. Codeine phosphate is an analgesic.
DOSAGE AND ADMINISTRATION
For Analgesia: Dosage should be adjusted according to the severity of the pain and the response of the patient.
Adults: 15 to 60 mg every 4 to 6 hours (usual adult dose, 30 mg).
Children: 1 Year of Age and Older – 0.5 mg/kg of b.d. weight or 15 mg/m2 of b.d. surface every 4 to 6 hours.
Soluble tablets codeine phosphate are administered subcutaneously or intramuscularly.
Solutions for injection should be prepared with sterile water and filtered through a 0.22 membrane filter.
Note: Do not use the solution if it is more than slightly discolored or contains a precipitate.
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